Octopus-like sucker may mean the end of many jabs for diseases such as obesity and breast cancer

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  • Sticky devices inspired by octopuses' tentacles could mean an extremity to injections 

By Roger Dobson

Published: 16:24 EST, 13 November 2023 | Updated: 16:24 EST, 13 November 2023

Sticky devices inspired by octopuses' tentacles whitethorn mean an extremity to injections for millions.

The patches person mini rubber suction cups and are designed to beryllium stuck connected to nan wrong of nan cheek, wherever they present insulin and different narcotics for obesity and bosom cancer, for instance, that are usually fixed by injection.

The style and size of a bean, nan patches could beryllium a boon for group whose medicine is not disposable successful pill form, arsenic good arsenic those pinch a needle phobia.

Many caller narcotics person to beryllium injected because they are made from proteins that would beryllium surgery down by nan enzymes successful nan digestive tract if taken successful a tablet. These 'large molecule' narcotics are besides often poorly absorbed into nan humor erstwhile taken arsenic pills. Delivering them done nan feature gets them straight into nan bloodstream.

Researchers person tried to present narcotics done patches placed wrong nan rima earlier but person struggled to get them to instrumentality to bedewed cheeks.

Sticky devices inspired by octopuses' tentacles whitethorn mean an extremity to injections for millions (File image) 

 Swiss scientists looked to octopuses, and their suckers, for inspiration. When nan octopus's sucker comes into interaction pinch its prey, nan sucker flattens, creating a watertight seal that holds it firmly successful place. The supplier transportation spot consists of a sucker, topped by a mini dome, which holds nan medicine, arsenic good arsenic a compound that increases nan permeability of nan feature tissue.

To use it, nan diligent presses it against nan soft, slippery aboveground of nan wrong of their cheek. This creates a vacuum that stops it from slipping off.

The suction cup past temporarily stretches nan lining of nan cheek, creating a bigger area done which nan narcotics tin beryllium absorbed: nan medicine past seeps retired of it and onto nan lining of nan cheek, wherever it is past absorbed into nan bloodstream.

The patches, which measurement 1cm by 0.6cm, would beryllium utilized erstwhile earlier being disposed of and a caller 1 applied erstwhile needed.

The patches person mini rubber suction cups and are designed to beryllium stuck connected to nan wrong of nan cheek, wherever they present insulin and different narcotics for obesity and bosom crab , for instance, that are usually fixed by injection

High-tech patch 

A high-tech spot could painlessly present medicine for excessive sweating. Excessive sweating (hyperhidrosis) tin beryllium treated pinch regular injections of Botox. But jabs tin beryllium painful. Researchers person developed a spot studded pinch mini biodegradable needles that dissolve aft injecting nan drug.

They could beryllium an 'effective, painless, inexpensive replacement to hypodermic injections erstwhile treating hyperhidrosis', researchers from Tehran University of Medical Sciences study successful nan diary Biomaterials Science.

In tests connected dogs, which person a akin feature lining to humans, nan patches successfully delivered drugs, including nan glucosuria and weight-loss medicine semaglutide (usually injected), to nan bloodstream.

The researchers, from ETH University successful Zurich, past asked 40 patient group to deterioration nan patches for half an hour. The patches, which contained h2o alternatively nan drugs, stuck good and only 1 subordinate said it felt uncomfortable. Most said they preferred them to injections, reported nan diary Science Translational Medicine.

'It's a method of delivering medications that could spare millions of group nan fearfulness and symptom associated pinch injections,' says Dr Nevena Paunović, 1 of nan researchers.

Further quality tests are planned. Commenting connected nan caller technique, James Birchall, a professor of pharmaceutical sciences astatine Cardiff University, said: 'The wrong lining of nan feature is little of a obstruction than nan tegument connected nan extracurricular of nan assemblage and is truthful perchance good suited to effective and convenient medicines delivery.

'This method avoids nan symptom of injection and nan request for a trained clinician to supply nan jab - and delivers nan medicine straight into humor vessels truthful it is not damaged by tummy acerb and enzymes.'


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