Does a blood transfusion pass on the donor's personality, too?

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Organ transplants and humor transfusions are undoubtedly lifesavers: past twelvemonth astir 4,600 group successful Britain received organ transplants, and astir 200,000 gallons of humor fixed successful transfusions.

But now immoderate scientists are starting to inquire whether thing unexpected whitethorn beryllium transmitted astatine nan aforesaid clip arsenic nan organ aliases transfusion.

It’s representation — some successful position of cells transmitting quality representation itself (i.e. preferences and characteristic traits), but besides individual cells carrying memories of damaging illness traits.

There person been well-publicised stories of group who’ve had organ transplants describing really abruptly they’ve knowledgeable characteristic changes, processing tastes they’d ne'er earlier had — successful nan U.S. a 47-year-old female had a lung transplant from an 18-year-old and developed a craving for brew and fried chicken.

Now humor transfusions, too, are thought by immoderate scientists to person this benignant of effect.

Last month, researchers astatine Karolinska Institute successful Sweden published a awesome study that suggests a origin of spontaneous encephalon haemorrhage could beryllium transmitted via humor transfusion.

Organ transplants and humor transfusions are undoubtedly lifesavers: past twelvemonth astir 4,600 group successful Britain received organ transplants, and astir 200,000 gallons of humor fixed successful transfusions

But now immoderate scientists are starting to inquire whether thing unexpected whitethorn beryllium transmitted astatine nan aforesaid clip arsenic nan organ aliases transfusion

The study, successful nan Journal of nan American Medical Association, recovered that patients who’d received humor from donors who later had recurring encephalon haemorrhages were much than doubly arsenic apt to suffer 1 themselves.

The researchers drew connected a Swedish-Danish database which contains accusation connected donors and patients receiving a transfusion from nan 1970s onwards — much than a cardinal patients were included.

The findings propose immoderate factors that tin springiness emergence to spontaneous encephalon haemorrhages tin beryllium dispersed done humor transfusion. However, arsenic only 0.1 per cent of nan donors successful nan study subsequently suffered recurring encephalon haemorrhages, this affected a mini number of patients.

Gustaf Edgren, an subordinate professor of epidemiology and 1 of nan researchers, said: ‘Blood transfusions are comparatively common, which makes antagonistic effects an important nationalist wellness issue.

‘However, it’s very improbable that you’d suffer a encephalon haemorrhage from thing transmitted done a transfusion.’

But why is it happening astatine all? The researchers are now readying to analyse samples from nan Danish Blood Donor Study biobank to spot if they tin place aberrant proteins associated pinch nan condition, which mightiness perchance beryllium damaging humor vessels.

READ MORE: Experts who deliberation humor transfusions could beryllium HARMFUL: More are being fixed than ever. But pinch perchance deadly side-effects, is it now clip to limit their use? 

However, different scientists person suggested that thing much subtle whitethorn beryllium down this — and immoderate spell overmuch further, suggesting that nan humor transfusion process whitethorn moreover transportation characteristic traits from philanthropist to recipient.

Five years ago, for example, a study by Geneva University reported really astir half of patients reported changes successful their behaviour and values aft receiving humor transfusions.

The researchers interviewed 7 group who’d received humor transfusions for orthopaedic surgery, specified arsenic hep replacements, and recovered 3 retired of 7 believed that their personalities had changed. One said he slept and dreamt a batch much than before; and different said his consciousness of sensation had been changed, which he recovered worrying, saying: ‘I dream that nan donor’s humor cannot return over.’

The 3rd diligent reported that aft nan transfusion he felt happier and stronger.

The authors concluded that: ‘Better knowing nan wave and value of these perceived changes is important arsenic physicians mightiness person to see specified accusation while getting consent for transfusion.’

Such beliefs whitethorn simply beryllium dismissed, nevertheless scientists studying an emerging section — called cellular representation — opportunity that personality-transference successful nan aftermath of organ transplant aliases humor transfusion is not specified fancy. In a 2019 article successful nan diary Medical Hypotheses, Dr Mitchell Liester, an adjunct objective professor of psychiatry astatine Colorado University, presented an thought that ‘memories from nan donor’s life are stored successful nan cells of nan donated bosom and are past “remembered” by nan recipient pursuing a transplant’.

If this sounds outlandish, 5 years ago, scientists reported they’d successfully transplanted memories from 1 snail into different by transplanting their tissues. The scientists gave mild electrical shocks to nan tails of a type of marine snail called Aplysia californica. These made nan snails’ protect withdrawal reflex — wherever they statement to protect themselves from harm — much pronounced.

The shocked snails had learnt to evade nan stimulus. Those that received nan shocks contracted defensively for 50 seconds erstwhile their tails were zapped, while those that hadn’t contracted for only 1 second. But aft nan unshocked snails were fixed transplants from nan shocked snails, they contracted for 50 seconds erstwhile zapped.

David Glanzman, a professor of biology astatine nan University of California, Los Angeles, who co-authored nan study, said nan consequence was ‘as though we transferred nan memory’.

Writing successful nan diary eNeuro, he explained that nan transplanted cells contained familial accusation called RNA, which is progressive successful various roles including really genes are switched connected aliases off.

Other scientists now propose that memories whitethorn beryllium stored arsenic chemic codes wrong nan proteins that our DNA is coiled around.

But whether this intends memories really are transferred successful humor transfusions aliases organ transplants remains to beryllium seen.