Cold and flu remedies made by likes of Sudafed and Nurofen should be pulled because they don't work, expert says... as French health chiefs urge public not to use ANOTHER decongestant over fears it could cause strokes

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Dozens of acold and flu remedies should beryllium pulled from shelves because they don't work, a starring master has claimed. 

US wellness officials person already ruled oral narcotics containing phenylephrine are 'not effective' decongestants aft reviewing decades of evidence. Nasal sprays packed pinch nan aforesaid constituent escaped nan judgement. 

The move could spot celebrated over-the-counter tablets and pills discontinued successful nan US, which would nonstop shockwaves done nan multi-million-pound industry.

Sudafed, Benadryl, Lemsip and Beechams each waste versions successful Britain for adjacent to £5. 

Own-brand narcotics from nan likes of Boots and LloydsPharmacy are besides available. 

US wellness officials person already ruled oral narcotics containing phenylephrine are 'not effective' decongestants aft reviewing decades of evidence. Nasal sprays packed pinch nan aforesaid constituent escaped nan judgement. The move could spot celebrated over-the-counter tablets and pills discontinued successful nan US, which would nonstop shockwaves done nan multi-million-pound industry. Pictured, 2 of nan narcotics taken orally containing phenylephrine

Brands for illustration Sudafed, Benadryl, Lemsip and Beechams each waste versions successful Britain for adjacent to £5. Own-brand versions from nan likes of Boots and LloydsPharmacy are besides available. Pictured, 2 of nan narcotics taken orally containing phenylephrine

Many are sold pinch different progressive ingredients specified arsenic paracetamol, which tin dainty symptoms that usually onslaught astatine nan aforesaid clip arsenic a stuffy nose. But UK regulators person yet to reappraisal nan ingredient, alternatively arguing 'no caller information concerns person been identified' moreover if nan grounds suggests they're nary amended than a placebo erstwhile it comes to clearing stuffy noses. Pictured, 2 of nan narcotics taken orally containing phenylephrine

Many are sold pinch different progressive ingredients specified arsenic paracetamol, which tin dainty symptoms that usually onslaught astatine nan aforesaid clip arsenic a stuffy nose.  

But UK regulators person yet to reappraisal nan ingredient, alternatively arguing 'no caller information concerns person been identified' moreover if nan grounds suggests they're nary amended than a placebo erstwhile it comes to clearing stuffy noses. 

Professor Ron Eccles, who ran the Common Cold Centre astatine Cardiff University earlier retiring from nan assemblage successful 2017, told MailOnline: 'Phenylephrine is an ineffective nasal decongestant erstwhile taken orally because it is metabolised successful nan gut and liver earlier it reaches nan nose. 

'My position is that [oral] phenylephrine products should beryllium discontinued successful nan UK arsenic they do not supply immoderate decongestion. 

'However, nasal decongestant sprays are effective and activity wrong minutes and nan decongestion lasts for 8 hours.'

SOME OF THE COLD AND FLU REMEDIES IN THE FIRING LINE

PHENYLEPHRINE 

Beechams Cold & Flu Hot Lemon & Honey

Nurofen Cold & Flu Relief

Benylin Cold & Flu Max Strength Capsules

Lemsip Cold & Flu Lemon 

Superdrug Max Strength Congestion Relief Capsules

Sudafed Congestion and Headache Relief Max Strength Capsules

Beechams All successful One Cold and Flu Tablets

Numark Max-Strength Cold & Flu Day & Night Capsules

Lemsip Max Day & Night Cold & Flu Relief Capsules

Boots Max Strength Sinus Pressure & Pain Relief Capsules

PSEUDOEPHEDRINE

Sudafed decongestant tablets 

Day & Night Nurse Cold and Flu

Benylin 4 Flu

Nurofen Cold & Flu 

Lloydspharmacy decongestant tablets

Care Decongestant Tablets 

Boots decongestant tablets 

Sinutab Non-Drowsy Congestion Relief 

Benadryl Plus Capsules 

Contac Non-drowsy Dual Relief Capsules 

PHOLCODINE

Boots Night Cough Relief Oral Solution 

Boots Day Cold & Flu Relief Oral Solution PL 

Care Pholcodine 5mg/5ml Oral Solution Sugar Free 

Covonia Dry Cough Sugar Free Formula 

Numark Pholcodine 5mg per 5ml Oral Solution 

Superdrug Pholcodine Linctus 

Strong Pholcodine Linctus BP

Day & Night Nurse Capsules

Day Nurse Capsules 

Thorrun Govind, erstwhile chair of nan Royal Pharmaceutical Society, said: 'A reappraisal connected its efficacy by nan MHRA fixed nan FDA consequence would beryllium helpful.' 

Sadik Al Hassan, superintendent pharmacist astatine PillTime, added: 'The merchandise is safe but has ever been known to person a constricted effect for congestion.'

It comes arsenic French officials this week besides urged group not to return communal nasal decongestant medicines containing a different but much effective constituent called pseudoephedrine complete imaginable consequence of strokes and bosom attacks. 

Christelle Ratignier-Carbonneil, head of France's National Agency for nan Safety of Medicines and Health Products (ANSM) said: 'The connection is clear — do not usage them. We do not consequence getting a changeable for a stuffy nose.'

In France, entree to pseudoephedrine was tightened backmost successful 2020 pursuing reports of superior adverse cardiovascular events. 

Concerns were first raised a decade earlier.

The European Medicines Agency (EMA) — which has nan powerfulness to rumor a prohibition — is presently carrying retired its ain probe into nan medicine's broadside effects, initiated astatine nan petition of ANSM. 

The EMA is expected to denote its proposal successful December. 

The Medicines and Healthcare products Regulatory Agency (MHRA), which polices nan information of narcotics utilized successful Britain, is simultaneously 'reviewing disposable evidence' to spot if waste rules successful nan UK request to change.

It could, successful theory, spot remedies made utilizing that — like Day & Night Nurse Cold and Flu and Benadryl Plus Capsules — pulled from shelves.    

Some countries, including nan US, person tougher stances connected pseudoephedrine owed to really easy it tin beryllium turned into meth.

UK officials restricted its waste successful 2008 complete nan aforesaid fears, forcing manufacturers to pivot to utilizing phenylephrine which cannot beryllium turned into nan people A drug.  

The ruling past period by a sheet of typical advisers to nan FDA found phenylephrine 'is not effective' astatine modular aliases moreover precocious doses erstwhile taken successful pill aliases liquid form.

This held existent erstwhile taken arsenic a standalone supplier aliases erstwhile successful operation pinch different ingredients.  

In nasal spray form, however, nan reviewers said phenylephrine does look to work. 

Briefing documents compiled by nan FDA show that little than one per cent of nan attraction of nan supplier is capable to scope nan chemoreceptor aft being surgery down successful nan gut.

The FDA could propulsion phenylephrine's approval, successful a move that could origin carnage for manufacturers who would person to region aliases reformulate their products.

Last week US drugstore concatenation CVS besides pulled oral meds that incorporate phenylephrine arsenic their only progressive ingredient.

Manufacturers declare phenylephrine eases nasal congestion by reducing swelling of nan mini humor vessels that beryllium wrong nan nostrils, making much abstraction for aerial to walk through. 

NHS watchdog, nan National Institute for Health and Care Excellence, states orally-administered decongestants 'may relieve nasal congestion successful nan short term'.

However, this effect 'does not widen past a fewer days, and nan use is comparatively small'.

CVS will statesman pulling celebrated oral cough and acold products pinch phenylephrine arsenic nan only progressive constituent from its shop shelves. Pictured: Empty CVS shelves successful New York past week

It comes arsenic French officials this week besides urged group not to return communal nasal decongestant medicines containing a different but much effective constituent called pseudoephedrine complete imaginable consequence of strokes and bosom attacks. Christelle Ratignier-Carbonneil, head of France 's National Agency for nan Safety of Medicines and Health Products (ANSM) said: 'The connection is clear — do not usage them. We do not consequence getting a changeable for a stuffy nose.' Pictured, 2 of nan narcotics taken orally containing phenylephrine

Manufacturers declare phenylephrine eases nasal congestion by temporarily shrinking nan mini humor vessels that beryllium wrong nan nostrils, making much abstraction for aerial to walk through. Dilated humor vessels tin origin nasal congestion. NHS watchdog, nan National Institute for Health and Care Excellence, states orally-administered decongestants 'may relieve nasal congestion successful nan short term'. However, this effect 'does not widen past a fewer days, and nan use is comparatively small'. Pictured, 2 of nan narcotics taken orally containing phenylephrine

HOW EXPERTS TREAT THEMSELVES 

Professor Ron Eccles, erstwhile head of nan Common Cold Research Centre astatine Cardiff University, says: 'I usage a nasal decongestant spray containing xylometazoline aliases oxymetazoline, arsenic they activity wrong minutes and nan effects past for up to 10 hours.'

Professor Penny Ward, a visiting professor successful pharmaceutical medicine astatine King's College London, says: 'I usually struggle done without taking anything, arsenic medicine only treats nan symptoms, not nan microorganism itself. But I mightiness sometimes return a Lemsip astatine nighttime to relieve nan symptoms and for comfortableness truthful I tin sleep.'

Professor Andrew Easton, a virologist astatine nan University of Warwick, says: 'I return over-the-counter products specified arsenic Beechams powders aliases akin if my symptoms are rather bad.'

Phenylephrine is not mentioned specifically successful nan guidance, isolated from to opportunity later it should not beryllium fixed to children nether six.

A 2008 reappraisal by nan MHRA recovered small impervious they worked successful kids. It recognised, however, that for illustration each supplier it tin origin broadside effects. 

Dr Alison Cave, MHRA main information serviceman told MailOnline: 'Patient information is our apical priority. All disposable information is cautiously considered erstwhile authorising immoderate medicine and we proceed to intimately show each medicines for information and effectiveness pursuing authorisation, to guarantee nan benefits outweigh immoderate risks.

'There person been nary caller information concerns identified pinch phenylephrine containing products and group tin proceed to usage arsenic directed.

'If you person immoderate concerns astir a medicine you are taking, please activity proposal from a healthcare professional.'

The Proprietary Association of Great Britain (PAGB), which represents companies making over-the-counter medicines, besides insisted patients should not beryllium concerned by nan FDA ruling.

Michelle Riddalls, its main executive, told MailOnline: 'Consumer information is paramount to our members, including those who manufacture products containing phenylephrine. 

'The products connected nan marketplace here, containing phenylephrine, are mixed pinch different progressive ingredients to supply nan champion imaginable denotation relief. 

'These products shape portion of a well-established cough, acold and flu offering wrong nan UK. 

'This ensures that these medicines are disposable and easy accessible to let consumers to self-care and dainty these wintertime ailments astatine location astatine a clip erstwhile nan NHS is nether a awesome woody of pressure.'

A British Retail Consortium spokesperson told MailOnline: 'Retailers will travel each guidance by nan MHRA connected issues relating to nan waste of medicines.' 

Meanwhile, Dr Leyla Hannbeck, main executive of nan Association of Independent Multiple Pharmacies, told MailOnline: 'These products person been disposable for galore years and safely supplied done pharmacies. 

'We person not had immoderate concerns raised astir these products from nan MHRA and arsenic specified if group who person been taking these products wish to proceed taking them these are available. 

'There are galore products complete nan antagonistic that tin thief pinch nasal congestions including saline sprays and nasal drops. 

'There are besides immoderate things that group tin do astatine location to relieve these symptoms including keeping hydrated, utilizing a lukewarm moist towel complete nan look and humidifiers tin help.' 

The FDA's ain ruling connected phenylephrine, however, is not nan first occasion questions person been raised complete nan effectiveness of over-the-counter acold remedies. 

In 2014, nan Cochrane Institute, which carries retired nan 'gold standard' of evidence-based reviews, recovered location was 'no bully grounds for aliases against nan effectiveness of complete nan antagonistic medicines successful acute cough' successful nan UK. Phenylephrine meds were among nan narcotics included. 

It comes arsenic nan UK medicines watchdog, successful March, besides ordered astir 20 over-the-counter cough medicines — including Day and Night Nurse and Boots Day Cold And Flu Relief — to beryllium withdrawn from nan market. 

Evidence was recovered that pholcodine, recovered successful nan cough syrups, could, successful uncommon cases, origin an allergic guidance if nan personification undergoes room and needs a wide anaesthetic which involves nan usage of a musculus relaxant.     

While it stressed specified reactions are incredibly uncommon — affecting astir 1 successful 10,000 procedures — nan reappraisal concluded nan benefits of pholcodine-containing cough and acold medicines 'do not outweigh nan accrued consequence of nan very uncommon arena of anaphylaxis'. 

Bosses astatine nan EMA besides recommended nan products' withdrawal from nan EU marketplace successful December past twelvemonth pursuing akin concerns.